A direct mode of virus inactivation
In the continuing R&D of the Sea-Aeration technology which catches and kills viral pathogens in the ventilation system. We bring new insights regarding its antiviral capacity. Our main component carrageenan, an ecological and natural product, shows great antiviral properties against enveloped viruses such as SARSCOV and influenza.
With the aid of partnering laboratory Avecom and the University of Ghent we had the following results:
The antiviral activity of carrageenan (the polysaccharide used as an active compound in our Sea-Aeration technology) against coronavirus was tested by Rega Institute (KU Leuven, Belgium). The results confirmed that the tested solution had antiviral activity against the human coronavirus OC43 with EC50 values in the range of 20-100 μg/mL. Interestingly, comparable results were also obtained when the antiviral activity of carrageenan was tested against the Influenza A virus. Showing effectiveness against enveloped viruses.
In collaboration with partnering laboratories and the University of Ghent, we have a proven 98 % reduction concentration of infectious viral particles (titer) against porcine reproductive and respiratory syndrome virus (PRRSV). This subfamily Coronavirinae in the family Coronaviridae shows sufficient similarities as to genome length and virion structure, for them to be expected to behave similarly outside their hosts.
The porcine reproductive and respiratory syndrome virus (PRRSV) was developed by Prof. Hans Nauwynck, the head of the Virology laboratory at the Faculty of Veterinary Medicine (Ghent University). Together with a group from the Department of Infectious and Parasitic Diseases, FARAH Research Centre, Faculty of Veterinary Medicine (Liege University) as a surrogate forSARS-CoV-2 (COVID19) virus was used. The incubation of PRCV with the carrageenan/product P emulsion resulted in a 98 % reduction concentration of infectious viral particles.
The full report is available on the TakeAirLabs website.